Clinical Update quiz
The Clinical Update online is a free member service providing up to 11 FREE CPD hours per year.
Each month, the Clinical Update is published online. There are 11 Clinical Updates per year (February - December). This service is available to ADAVB and ADATas members only. Members can log in to view and answer the Clinical Update questions. If you answer at least eight out of 10 questions correctly, you will receive one hour of scientific CPD.
Please note: Each new Clinical Update will be available below from the first business day of each month.
ADAVB Clinical update October 2026.
Long-term outcomes of regenerative periodontal therapy and orthodontic treatment: 20-year results from a prospective study. Roccuzzo A, Li Y, Salvi GE, Stähli A, Imber J JC, Roccuzzo M. J Dent. 2026 Oct:173:106799. doi: 10.1016/j.jdent.2026.106799. Epub 2026 May 28.
Introduction
Advanced periodontitis often results in pathologic tooth migration which may appear as tooth drifting, flaring and spaces resulting in aesthetic problems for the patient. The management of severely periodontally compromised teeth is a clinical challenge in periodontal, orthodontic and prosthetic treatment.
Orthodontic tooth movement in the presence of active periodontitis can worsen the microbial biofilm-induced inflammation, leading to accelerated attachment loss. This has been shown in animal studies. Orthodontic tooth movement has been demonstrated to be safe once the periodontal inflammation has been controlled. The European Federation of Periodontology (EFP) S3 clinical guidelines support the requirement that orthodontic treatment must be performed on a periodontally stable and healthy dentition. In the case of teeth with deep intrabony defects, periodontal regeneration using enamel matrix derivative (EMD) in combination with or without bone grafting materials is a reliable long-term treatment modality.
The orthodontic-periodontic approach aims to correct malocclusion, aesthetics and also create an anatomically and functionally sustainable dentition. Case series and pilot studies by other authors have shown the feasibility of moving teeth into regenerated or grafted defects. There are limited long-term studies of the outcomes beyond a decade. The aim of this study was to review the 20-year clinical outcomes of a consecutively enrolled cohort of patients treated for periodontitis using a regenerative approach, followed by orthodontic treatment and tailored supportive periodontal care (SPC).
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